Novel approaches to selective treatments of human solid tumors

Developed from the proceedings of the workshop (on title), held in Annapolis, Maryland, June 1990, to bring together scientists from diverse disciplines in cancer biology, epidemiology, molecular biology, genetics, immunology, gerontology, and drug resistance to discuss the possible underlying factors that may account for the increase in cancer incidence and mortality among the elderly. The 23 papers are organized in sections devoted to background, genetics and epigenetics, influence of physiological changes in the immune constitutions in aging and cancer, molecular biology of age-related changes in some types of cancer (breast cancer, prostate cancer), molecular epidemiology and treatment modality in patients of different ages with leukemias, drug resistance, and summation and synthesis.